Technician - Technology and Process Innovation

As an integral member of the Technology and Process Innovation (TPI) team, this role will work across a range of cell and gene therapy focused projects providing research support for both process optimisation and analytical development. This role will provide access and training on the latest technologies used for bioprocess automation and experience in the use of a range of analytical techniques.

A Technician within the TPI team will take responsibility for the day-to-day planning and execution of laboratory-based tasks to assist senior team members to deliver projects to agreed timelines and budgets.

Key Accountabilities:

  • Perform laboratory-based activities to contribute to the development of research-based manufacturing processes. An understanding of ATMP process development workflows would be advantageous.

  • Laboratory-based activities can include but are not limited to media and reagent preparation, stock management, culture of various cell types and performing routine assays such as flow cytometry, qPCR, ddPCR, ELISA, MADLS, LC-MS, cell-based viral transduction assays and other cell-based assays.

  • Work closely with all relevant internal and external stakeholders to ensure successful delivery of projects.

  • Support laboratory operations by operating under aseptic technique, ensuring adequate reagent supply and that equipment is safe, calibrated, and ready to use.

  • Adhere to the company’s health and safety policies, be able to comply with quality management system procedures and electronic laboratory notebook (eLN) for data capture.


Experience:

  • Technical knowledge in bioprocessing, biologics, molecular biology, cell biology, analytical assays or assay development is required.

  • More specifically, a background in virology, biochemistry, cell biology or other related life science discipline is essential.

  • 1-3 years’ relevant experience working within a research or industry-based manufacturing environment either with biologics or cell therapies.

  • Cell culture experience with a range mammalian cell types would be advantageous.

  • Experience of at least one of the following analytical techniques is essential: flow cytometry, qPCR, ddPCR, ELISA, MADLS, LC-MS or cell-based assays.

  • Experience of analysing experimental data independently, particularly for analytical assays, would be advantageous.


Knowledge / Skills / Competencies:

  • Highly motivated, pragmatic and practical to support the mission of the Cell and Gene Therapy Catapult to accelerate the development of a commercial cell and gene-based therapy industry in the UK.

  • Desire to establish a high-profile career within cell and gene sector and the personal drive to help push the sector to be a commercial success.

  • Strong interest in cell and gene therapies.

  • High level interpersonal, communication (oral and written) skills and emotional intelligence.

  • Ability to work well under pressure, to work independently and to be able to take the initiative when completing tasks.

  • Excellent organisational skills, ability to manage the workload from multiple assigned tasks.

  • Driven in delivering objectives with good quality and on time.

  • Ambitious, collaborative, driven.

  • Comfortable operating autonomously once goals and objectives are set.

  • Good oral communication skills including project team updates through PowerPoint presentations to the senior group.

  • Good written communication skills including report writing, data presentation and protocol writing.

  • Ability to maintain accurate and detailed records.

  • Good IT skills including experience of data analysis and structure (such as GraphPad Prism and FlowJo).

  • Experience of laboratory equipment calibration and maintenance.

  • Sound understanding of good stock maintenance.

  • A good team player but also able to work independently.

  • A positive attitude towards learning, personal and professional development.

  • Keeps up to date with professional knowledge, expertise and best practice.

  • Willingness to travel.


Education / Qualifications:

  • BSc within a Life Sciences discipline.


CGT Catapult is committed to providing an equal, diverse, and inclusive work environment where everyone’s contributions are valued. We celebrate differences, empower, and inspire everyone, because when everyone is included, everyone wins. In 2024, we received Bronze accreditation from Inclusive Employers.