Translational Pathways in Gene and Cell Therapy

We invite you to attend our seminar on translational pathways for cell and gene therapy, organised by the MRC Centre of Research Excellence (CoRE) in Cardiac Therapies, and the MRC CoRE in Therapeutic Genomics, in collaboration with the Cell and Gene Therapy Catapult (CGT Catapult). This seminar will provide key insights on:

• The expertise and resources that the CGT Catapult can provide to help you develop a clinically and commercially viable cell or gene therapy,
• Key considerations from across the cell and gene therapy lifecycle for translating your research, including: Navigating the complex regulatory landscape for cell and gene therapies; Non-clinical considerations, such as safety strategies; Health economics and market access analysis that can help inform downstream cell or gene therapy clinical development and reimbursement.
• The common challenges associated with developing and manufacturing a cell or gene therapy.
• The development path taken by a pioneering gene/cell therapy developed at the University of Oxford.
• Intellectual Property (IP) and commercialisation considerations by the local TTO and/or MRC CoRE researchers and clinicians working on cell or gene therapies, or technologies that facilitate their development, are invited to attend this free event. You will have the opportunity to meet experts in cell and gene therapy development, share ideas, and learn more about the available support to rapidly progress your research towards patient benefit. ​

Agenda

09:45 – 10:00 | Introduction to cell and gene therapies and the CGT Catapult
CGT Catapult and Local TTO
10:00 –10:30 | Navigating the regulatory pathway to first-in-human clinical trials (and beyond)
Dr Rehma Chandaria, Head of Regulatory Affairs, CGT Catapult
10:30 –11:00 | Non-clinical considerations for stem cell therapeutics
Dr Keith McLuckie, Head of Nonclinical, CGT Catapult
11:00 –11:30 | Networking break
12:00 –12:30 | Talk from a local collaborator
11:30 –12:00 | How can health economics help development and why you should consider reimbursement earlier rather later
Dr Laura Beswick, Head of Health Economics, CGT Catapult
12:30 –13:30 | Lunch
13:30 –14:00 | Gene Therapy process and product development: Where to begin?
Dr Maria Barreira, Head of Gene Modification, CGT Catapult
14:00 –14:30 | Next steps and support for translational research
Local TTO
14:30 –15:00 | Refreshments and networking
15:00 –17:00 | Pre-arranged 1-2-1 meetings with CGT Catapult, Local TTO and TRO

If you are a MRC CoRE or University of Oxford researcher or clinician working in cell or gene therapy research and on the translational pathway and would like to register for a 1-2-1 meeting with a representative from the CGT Catapult, Local TTO or TRO, please indicate this in your ticket registration form. Meetings will occur from 14:00-16:00 on the day of the event.

• The Local TTO can advise on any queries related to IP, third-party funding rights, patent filing, legal agreements (including NDAs), technology licencing and spinouts.
• The Local TRO can advise on funding opportunities and tailoring applications for the right funding.
• CGT Catapult can provide support at every step of your journey to develop your cell or gene therapy, including non-clinical safety considerations, manufacturing process development, regulations, and health economics.

Who should attend?

• Principal Investigators (PIs) and Research Fellows from the MRC CoREs in Cardiac Therapies and Therapeutic Genomics
• Principal Investigators (PIs) and Research Fellows from the host university and affiliated research institutes
• Clinician scientists and translational researchers
• Technology Transfer Office (TTO) and Technology Research Office (TRO) professionals
• Postdoctoral researchers (subject to availability) - not entirely sure how to manage this one- open to your thoughts .
• PhD students (subject to availability)

1-2-1 meetings will be subject to availability, and attendees that secure a meeting slot will be notified of the timing, location and the team they will be meeting with (CGT Catapult and Local TTO and/or TRO) in advance of the event. Meeting slots are limited to 20 minutes to ensure there is enough time to speak to all registered attendees.