De-risking innovation: How translational and regulatory readiness shape investor confidence in ATMPs

The UK continues to be recognised as a global leader in cell and gene therapy, supported by a regulatory environment that balances scientific rigour with adaptive flexibility. The Centre of Excellence in Regulatory Science and Innovation for Advanced Therapies (CERSI-AT) is a central component of this national strategy and aims to strengthen the UK’s regulatory ecosystem and support the translation of advanced therapies from research to clinical deployment.

A key gap identified by CERSI-AT concerns the limited clarity around investor expectations for therapy developers to demonstrate translational readiness across scientific, regulatory, and market access perspectives. 

In this whitepaper, CERSI-AT shares findings from in-depth interviews conducted with three leading UK investment firms active in the ATMP sector, exploring how these investors evaluate opportunities and the extent to which regulatory considerations influence their decisions.

Read the full whitepaper