Digital innovation
We are driving the development and implementation of innovative digital technologies to enhance manufacturing efficiency, precision and scalability. These advancements are critical to reducing development costs and increasing global patient access to advanced therapies.
Benefit from our expertise in:
Process Analytical Technologies (PAT)
Our experts can support you to optimise your ATMP development processes through advanced control and monitoring solutions. Through our state-of-the-art Process Analytical Technologies Laboratory, we can support the integration of in-line, on-line, and at-line analytical technologies to enhance your process understanding and monitoring.
Benefit from our expertise in:
- Bespoke integration of innovative biosensors and analytical technologies into ATMP development processes
- Chemometrics and soft sensor development
- Integration of automated sampling for high-volume data generation
- Expert process and analytical knowledge across all cell and gene therapy modalities
Process modelling
Our data scientists can leverage rich process datasets and combine PAT data with off-line analytics to generate complex dynamic process models. We can implement these in-process to help you establish your own advanced model-prediction and control strategies.
Benefit from our expertise in:
- Experimental design, leveraging Design of Experiment (DoE) approaches and statistical analysis to gain the maximum information from bioprocessing runs for modelling
- Structured data collection through automated, compliant digital platforms for bioprocess development
- Generation of mechanistic and hybrid models leveraging deep analytical characterisation to enhance process understanding and formalise the relationship between critical process parameters (CPPs) and critical quality attributes (CQAs)
- Generation of PAT data models, including chemometric models to enable process monitoring
- Digital twin development of your bioprocess for closed-loop control strategies, including model-predictive control based on real-time PAT data collection
- Extensive multimodality data libraries to support process modelling and soft sensor development
Digital connectivity
We can integrate, connect and optimise digital technologies across your bioprocessing operations to enable seamless communication, advanced process control and efficient information management.
Benefit from our expertise in:
- Establishing robust interconnectivity between digital platforms to ensure a cohesive and efficient operational ecosystem
- Deploying digital platforms, including Electronic Lab Notebooks (ELN), Process Information Management Systems (PIMS), Supervisory Control and Data Acquisition (SCADA), and electronic Batch Manufacturing Records (eBMR), for comprehensive digital oversight and management
- Streamlining data capture, analysis, and reporting to support rapid in-process decision-making
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Working on a cell or gene therapy innovation challenge?
Contact us today to find out how we can support you.